Exploiting increased autophagy in bronchial epithelial cells: a new therapeutic approach for chronic obstructive pulmonary disease (COPD) [ 2016 - 2018 ]

Research Grant

Researchers: Prof Sandra Hodge (Principal investigator) ,  Dr Peter Zalewski

Brief description COPD is incurable, a leading cause of death, and new therapies are urgently needed. Autophagy is a cell response to cell stress conditions, however increased autophagy is harmful. We will investigate the association of increased autophagy with COPD and smoking and evaluate therapies that can reduce autophagy, including zinc-related drugs and novel antibiotics that have been modified to lose their anti-bacterial activity.

Funding Amount $AUD 745,390.84

Funding Scheme Project Grants

Notes Standard Project Grant