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Expansion, Differentiation and Functional Analysis of In Vitro Derived Pdx1+ Pancreatic Progenitors [ 2008 - 2010 ]

Also known as: Differentiation of Pancreatic Beta Cells In Vitro

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/519502]

Researchers: Prof Edouard Stanley (Principal investigator) ,  Prof Andrew Elefanty

Brief description Type 1 diabetes is a condition that arises when the body's immune system destroys insulin-producing beta cells within the pancreas. Recent studies have shown that normal glucose control can be restored by replacing the missing beta cells by transplantation of cells from deceased donors. However, the demand for transplant material outweighs supply. The work described in this application seeks to define how insulin-producing beta cells can be derived in the laboratory from embryonic stem cells .

Funding Amount $AUD 540,075.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Identifiers
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ACN 633 798 857