Examining the role of extracellular myeloperoxidase in the pathogenesis, identification and treatment of high-risk unstable and ruptured atherosclerotic plaque [ 1/1/2021 - 4/30/2023 ]

Research Grant

Brief description Vascular inflammation has emerged as a key driver and therapeutic target for stroke and heart attack. Existing diagnostic techniques and treatments do not target inflammation so that residual inflammatory risk remains. There is a need to identify patients with active inflammation who may benefit from treatment. Myeloperoxidase is an inflammatory enzyme abundant in plaque at risk of rupture and subsequent stroke or heart attack and presents as a potential diagnostic tool and therapeutic target.

Funding Amount $103,356

Funding Scheme Postgraduate Scholarships

Chief Investigator Dr James Nadel

Notes Clinical Medicine and Science Research Scholarship