Evolutionary genomics approaches for studying acquisition of drug resistance in tumours [ 2013 - 2017 ]

Research Grant

[Cite as]

Researchers: Dr David Goode (Principal investigator)

Brief description Chemotherapy often fails because some of the cells in tumour evolve resistance to the drugs the patient is given, causing relapse. We study how a tumour’s unstable genome and high rate of mutation drives its evolution by observing tumour cells in the laboratory as they evolve resistance to drugs and the genetic differences between resistant and sensitive cells. This work will help develop therapeutic strategies to prevent tumours from evolving resistance to chemotherapy.

Funding Amount $AUD 313,390.46

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF

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