grant

Evolution of pertussis epidemics and effect of genotypes on infection outcomes and immunisation [ 2011 - 2014 ]

Also known as: Whooping cough epidemics: effect of strains on severity of infection and immunisation

Funded by National Health and Medical Research Council
Managed by The University of New South Wales
Managed by University of New South Wales
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1011942]

Researchers: A/Pr Ruiting Lan (Principal investigator) ,  A/Pr Nicholas Wood ,  Prof Gwendolyn Gilbert ,  Prof Helen Marshall ,  Prof Peter Mcintyre
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Brief description Pertussis, or whooping cough, is caused by Bordetella pertussis. Despite high vaccine coverage, the incidence of pertussis has increased substantially in recent years in Australia. One of the contributing factors is changes in the pertussis strains. This project will determine the genetic composition and virulence characteristics of epidemic strains in Australia and investigate the effect of these strains on disease severity and vulnerability of vaccinated individuals to infection.

Funding Amount $AUD 657,781.42

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Medical and Health Sciences | Medical Microbiology | Medical Bacteriology | genomics | infectious diseases | molecular epidemiology | pertussis | vaccine-preventable diseases |
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