grant

Evolution and function of a novel lateral flagellar locus, Flag-2, in pathogenic Escherichia coli [ 2009 - 2011 ]

Also known as: How bacteria grow in the gut

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/566883]

Researchers: Prof Elizabeth Hartland (Principal investigator) ,  A/Pr Scott Beatson ,  Prof Gad Frankel

Brief description This project will study how the bacteria that cause infant diarrhoea colonize the intestine and induce disease. We have identified a novel genetic region that allows E. coli to survive and persist in the intestine. Similar genes are also present in closely related organisms. This project will help us to undestand how new diseases evolve and emerge and may lead to the development of new vaccines to protect against infant diarrhoea.

Funding Amount $AUD 465,158.14

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Allergy | Biomedical and Clinical Sciences | Bacterial pathogen | Host-pathogen interactions | Immunology | Intestinal colonization | bacterial gastroenteritis | diarrhoea | inflammation | mucosal inflammation |
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