Evaluating the link between the GPR91 receptor and renin in the pathogenesis of diabetic retinopathy [ 2011 - 2013 ]

Research Grant

Researchers: Prof Jennifer Wilkinson-Berka (Principal investigator) ,  A/Pr Janos Peti-Peterdi ,  Dr Antonia Miller

Brief description Diabetic retinopathy is the leading cause of blindness in people of working age. A hormonal system called renin-angiotensin is implicated in the development of diabetic retinopathy, and new evidence indicates that its blockade improves aspects of the disease. This project will examine if succinate/GPR91 mediates the over production of renin and represents an additional target for the treatment of diabetic retinopathy.

Funding Amount $AUD 486,824.89

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant