Can esomeprazole improve outcomes in women at high risk of pre-eclampsia? A Phase II placebo-controlled randomised, multi-centre clinical trial. [ 2018 - 2020 ]

Research Grant

Researchers: Prof Jon Hyett (Principal investigator) ,  A/Pr Fabricio Da Silva Costa ,  Dr Natalie Hannan ,  Prof Gustaaf Dekker ,  Prof Jonathan Morris
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Brief description Pre-eclampsia, recognised through the development of high blood pressure in pregnancy, causes death and/or injury to mothers and babies. An improved understanding of the development of pre-eclampsia has provided opportunities for early prediction and prevention of disease. We will use a powerful predictive model to identify pregnancies at high risk of pre-eclampsia then observe the effect of a novel treatment (esomeprazole) on maternal blood pressure and the development of this disease.

Funding Amount $AUD 1,619,484.64

Funding Scheme Project Grants

Notes Standard Project Grant