Epithelial Drivers of Neutrophil Plasticity in Early Cystic Fibrosis Lung Disease [ 2018 - ]

Research Grant

Researchers: Dr Luke Garratt (Principal investigator) ,  A/Pr Anthony Kicic ,  Asst Prof Rabindra Tirouvanziam ,  Prof Stephen Stick

Brief description Why airway inflammation becomes chronic so early in life for people with cystic fibrosis (CF) is unclear. This project will use the latest techniques to characterise immune cells found in airways of infants with CF and model in the laboratory how immune cells react to the CF airway. We will challenge CF airway cells with different bugs that can infect the lung, then see if the responses by CF airway cells can change the normal response of immune cells, triggering chronic disease.

Funding Amount $849,462.00

Funding Scheme Project Grants

Notes Standard Project Grant