EPIGENETIC REPROGRAMMING OF MALIGNANT BREAST CANCER [ 2014 - 2018 ]

Research Grant

Researchers: A/Pr Pilar Blancafort (Principal investigator) ,  A/Pr Killugudi Swaminatha-Iyer ,  Prof Ryan Lister

Brief description Poorly differentiated breast cancers are aggressive tumors, frequently resistant to chemotherapy and associated with high morbidity. Herein we propose the engineering of more selective therapeutic agents able to target the genes involved in cancer initiation and resistance to treatment. We aim to correct and reprogram the cancer cell genome in state that is similar to normal, not tumorigenic cells. This work will generate novel forms of treatment for cancers that are presently not curable.

Funding Amount $AUD 863,268.57

Funding Scheme Project Grants

Notes Standard Project Grant