Epigenetic reprogramming of calcified vascular smooth muscle cells as a treatment for vascular calcification [ 1/1/2022 - 12/31/2025 ]

Research Grant

Brief description Pathological hardening of blood vessels, or vascular calcification, is a frequent and deadly complication of many cardiovascular disorders. It is caused by the irreversible change in mature vascular smooth muscle cells (the main cell type in the blood vessel walls) to a bone-forming cell type. We have now identified a new gene that can potentially revert calcified vascular cells back to their physiological state. This represents a promising new approach for treatment of vascular calcification.

Funding Amount $1,285,195

Funding Scheme Ideas Grants

Chief Investigator Dr Renjing Liu

Notes Ideas Grants