Epigenetic regulation of inflammatory genes in the fetal membranes: role in term and preterm birth [ 2015 - 2018 ]

Research Grant

Researchers: Prof Tamas Zakar (Principal investigator) ,  Prof Jonathan Hirst ,  Prof Murray Mitchell

Brief description Preterm birth is the leading cause of death among newborns and the biggest contributor to disability among infants. Here we propose research to define the mechanism that controls the length of pregnancy and is disrupted in preterm birth. Specifically, we will determine what causes the repression of the labour-promoting inflammatory genes in the uterus during pregnancy and what activates them at labour. We will identify new targets for interventions to block or prevent preterm birth.

Funding Amount $AUD 468,534.82

Funding Scheme Project Grants

Notes Standard Project Grant