grant

Epigenetic regulation of CD8+ T cell function and memory. [ 2011 - 2013 ]

Also known as: Molecular control of virus-specific T cell responses.

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1003131]

Researchers: Prof Stephen Turner (Principal investigator) ,  Prof Sudha Rao

Brief description Upon virus infection, a subset of white blood cells, called killer T cells, are recruited to fight the infection. This proposal aims to examine molecular changes that occur within killer T cells and impart their specific function. We also aim to understand how killer T cells are _programmed� as they establish immunological memory. This proposal will provide insights important for the design and improvement of vaccine strategies to fight pathogens such as influenza, HIV and even tumors.

Funding Amount $AUD 578,171.77

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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Subjects
Cellular Immunology | Immunology | Medical and Health Sciences | T cell memory | T cell response | cytotoxic T lymphocyte (CTL) activation | cytotoxic T lymphocytes (CTL) | epigenetics | immunity | influenza | memory T-cells |
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