grant

Epigenetic mechanisms of dysregulated immune function in autoimmune and allergic disease of childhood [ 2017 - 2019 ]


Funded by National Health and Medical Research Council
Funded by National Health and Medical Research Council (Australia)
Funded by National Health and Medical Research Council (NHMRC)
Managed by The Walter and Eliza Hall Institute of Medical Research
Managed by Walter and Eliza Hall Institute
Provided by   National Health and Medical Research Council

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/1129033]

Researchers: Prof Leonard Harrison (Principal investigator) ,  A/Pr Alicia Oshlack ,  Dr Yuxia Zhang ,  Prof Anne-Louise Ponsonby ,  Prof Jennifer Couper
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Brief description The rising incidence of autoimmune and allergic diseases is ascribed to the environment, which can modify the chemistry of DNA and how our genes work (epigenetics). We aim to identify epigenetic changes in immune cells in infants at risk for type 1 diabetes and food allergy followed from birth. This may reveal both general and disease-specific levels of epigenetic-immune dysregulation and is a foundation on which to understand potentially modifiable environment-gene interactions.

Funding Amount $AUD 463,101.37

Funding Scheme Project Grants

Notes Standard Project Grant

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Subjects
Clinical Sciences | Clinical Sciences Not Elsewhere Classified | Medical and Health Sciences | child health | epigenetics | food allergy | immunology | type 1 diabetes mellitus (insulin-dependent diabetes mellitus) |
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