Epigenetic mechanisms of brain dysfunction in psychotic and mood disorders [ 2015 - 2018 ]

Research Grant

Researchers: A/Pr Melissa Green (Principal investigator) ,  Dr Sarah Cohen-Woods ,  Prof Murray Cairns

Brief description This project investigates the role of epigenetic processes (i.e., functional changes to the genome affecting gene expression) in mediating the long-term effects of childhood trauma in schizophrenia and bipolar-I disorder. We specifically aim to distinguish the effects of trauma-related epigenetic effects on brain structure and function, and on the immune and stress-response systems, and the potential moderation of these effects by structural genetic variants associated with psychosis risk.

Funding Amount $AUD 617,836.95

Funding Scheme Project Grants

Notes Standard Project Grant