Enterovirus 71 in the Asia-Pacific region: reverse genetic approaches to virus surveillance and vaccine development. [ 2004 - 2009 ]

Research Grant

Researchers: Prof Peter Mcminn (Principal investigator) ,  Dr Andrew Kiyu ,  Prof Mary Cardosa

Brief description In this research the team will use advanced biotechnological techniques to study the distribution and virulence markers of an important emerging infectious disease, enterovirus 71 encephalitis, in the Asia-Pacific region. The knowledge and technical advances derived from this study will be shared with neighbouring countries in order to conduct sensitive surveillance for this infection throughout the region. The study's other major aim is to use cutting-edge biotechnological techniques to develop a genetically defined, live attenuated vaccine strain. Candidate vaccine strains will be tested for their effectiveness in both cell culture-based and animal models.

Funding Amount $AUD 690,833.80

Funding Scheme NHMRC Strategic Awards

Notes International Collaborative Research Grant