Enhancing vaccine efficacy by harnessing dendritic cell receptors and their unique properties [ 2014 - 2016 ]

Research Grant

Researchers: A/Pr Irina Caminschi (Principal investigator) ,  A/Pr Scott Mueller ,  Prof William Heath

Brief description Potent vaccination might be achieved by using monoclonal antibodies as magic bullets to target vaccines to special cells in the body. We show that targeting these special cells by using monoclonal antibodies that recognise Clec9A is effective, perhaps because it brings several different immune cells together so that they orchestrate very efficient immune responses. This application investigates how targeting Clec9A allows strong vaccination so that we can apply this to new generation vaccines.

Funding Amount $AUD 687,519.82

Funding Scheme Project Grants

Notes Standard Project Grant