Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/595300]Researchers: Prof Ralph Martins (Principal investigator) , Kevin Taddei , Prof Mathew Martin-Iverson
Brief description Amyloid-beta (abeta) accumulation in the brain is a key step in the development of Alzheimer's disease, with potential therapies focusing on its clearance. Compounds that bind abeta in blood have been shown to alter brain abeta levels. We will assess the efficacy of a novel abeta-binding peptide to promote peripheral clearance of brain-derived abeta in a mouse model of AD. Such a drug would be effective in sporadic AD, where the efflux transport, clearance and degradation systems are defective.
Funding Amount $AUD 548,681.34
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 595300
- PURL : https://purl.org/au-research/grants/nhmrc/595300
