grant

Enhanced and highly specific delivery of small interfering RNA and oligonucleotides as therapeutics for gene silencing [ 2013 - 2016 ]

Also known as: Specific targeted delivery of gene therapeutics by employing polymeric carriers to treat liver related diseases

Funded by National Health and Medical Research Council
Managed by University of Technology Sydney
Managed by University of Technology, Sydney
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1054011]

Researchers: Dr Simon Ting (Principal investigator)

Brief description This proposal aims to develop glyco-nanocarriers for the efficient and specific delivery of siRNA/oligonucleotides to treat liver diseases. Complex glycopolymer architectures developed here will protect desired genes from enzymatic degradation and will deliver the gene to the liver specifically for therapy, hence providing a solution towards nucleic acid therapy.

Funding Amount $AUD 311,860.82

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF

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Subjects
Biomedical Engineering | Biomaterials | Engineering | RNA | binding protein | biomaterials | drug delivery systems | gene delivery | liver disease | polymerisation |
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ACN 633 798 857