Engineering MYCN models of high-grade serous ovarian cancer (HGSC) [ 2016 - ]

Research Grant

Researchers: Prof Clare Scott (Principal investigator) ,  A/Pr Ronny Drapkin ,  Dr Matthew Wakefield

Brief description The most lethal type of ovarian cancer, high-grade serous cancer (HGSC), can be divided into four subtypes based on gene patterns. One subtype involves a set of genes/proteins that, in their specific combination, result in activation of a pathway known as MYCN. As most HGSC start in the fallopian tube, we are using fallopian tube material to make new MYCN HGSC models to observe development in the earliest stages. We hope to generate new tests and treatments for this subtype of ovarian cancer.

Funding Amount $797,478.00

Funding Scheme Project Grants

Notes Standard Project Grant