Endosomal sorting of amyloid precursor protein in Alzheimer's disease [ 2014 - 2017 ]

Research Grant

Researchers: A/Pr Brett Collins (Principal investigator) ,  A/Pr Rohan Teasdale ,  Prof Elizabeth Coulson ,  Prof Glenn King ,  Prof Wanjin Hong

Brief description Alzheimer's Disease is a progressive neurological disorder and is the most common cause of dementia. Effective treatments are desperately needed, but none are currently available. The toxic amyloid peptide A? is central to disease pathology and is derived from breakdown of the Alzheimer’s amyloid precursor protein (APP). In this project we will examine the interactions between APP and the molecular machinery that controls its location in the cell and subsequent degradation.

Funding Amount $AUD 858,643.66

Funding Scheme Project Grants

Notes Standard Project Grant