Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1047554]Researchers: A/Pr Stephen Ting (Principal investigator) , A/Pr David Curtis
Brief description Self-renewal allows normal haematopoeitic stem cells to constantly replenish the blood system. Conversely, leukemia stem cells use self-renewal to propagate the disease, and utilise the quiescence phase to evade treatment eradication. We identified that the endocytic gene, Ap2a2 enhances haematopoeitic stem cell self-renewal. Through Ap2a2, we are now investigating the role of endocytosis and self-renewal in leukemia and ex vivo expansion of human haematopoietic stem cells.
Funding Amount $AUD 548,258.76
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1047554
- PURL : https://purl.org/au-research/grants/nhmrc/1047554
