Elucidating the role and potential for therapeutic targeting of TLR7 in emphysema and COPD [ 2018 - 2021 ]

Research Grant

Researchers: Prof Philip Hansbro (Principal investigator) ,  Prof Ian Adcock ,  Prof Peter Wark

Brief description Emphysema is a major cause of illness and death and there are no effective treatments. It is caused by smoking that damages the airways and air sacs but how this occurs is not well understood. We have found that a new factor, called Toll-like receptor 7, is involved in emphysema. In this study we will now characterise its roles in this disease, work out how it induces emphysema and test new inhibitors (antibodies) that we have developed as treatments.

Funding Amount $AUD 938,740.92

Funding Scheme Project Grants

Notes Standard Project Grant