Data

Electrophysiology dataset describing function of hERG potassium channels expressed in HEK cells

University of New South Wales
Ng, Chai Ann ; Farr, Jessica ; Young, Paul ; Windley, Monique ; Perry, Matthew ; Hill, Adam ; Vandenberg, Jamie
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ctx_ver=Z39.88-2004&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Adc&rfr_id=info%3Asid%2FANDS&rft_id=info:doi10.26190/7tqy-gc11&rft.title=Electrophysiology dataset describing function of hERG potassium channels expressed in HEK cells&rft.identifier=https://doi.org/10.26190/7tqy-gc11&rft.publisher=UNSW, Sydney&rft.description=High-throughput patch clamp electrophysiology dataset acquired on Nanion syncropatch 384PE platform describing voltage dependent gating of hERG potassium channels expressed in HEK cells. Specific voltage protocols: 1) Steady state activation 2) Steady state deactivation 3) Onset of inactivation This example dataset accompanies the methods paper: Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology by Chai-Ann Ng, Jessica Farr, Paul Young, Monique J. Windley, Matthew D. Perry, Adam P Hill, View ORCID ProfileJamie I Vandenberg. Preprint available at : https://doi.org/10.1101/2021.02.02.427891&rft.creator=Ng, Chai Ann &rft.creator=Farr, Jessica &rft.creator=Young, Paul &rft.creator=Windley, Monique &rft.creator=Perry, Matthew &rft.creator=Hill, Adam &rft.creator=Vandenberg, Jamie &rft.date=2021&rft.relation=10.1093/biomethods/bpab003&rft.relation=10.1101/2021.02.02.427891&rft_rights= https://creativecommons.org/licenses/by/4.0/&rft_subject=electrophysiology&rft_subject=ion channel&rft_subject=hERG&rft_subject=cardiac arrhythmia&rft_subject=patch clamp&rft_subject=Animal Physiology - Biophysics&rft_subject=BIOLOGICAL SCIENCES&rft_subject=PHYSIOLOGY&rft_subject=Cardiology (incl. Cardiovascular Diseases)&rft_subject=MEDICAL AND HEALTH SCIENCES&rft_subject=CARDIORESPIRATORY MEDICINE AND HAEMATOLOGY&rft_subject=Cardiovascular System and Diseases&rft_subject=HEALTH&rft_subject=CLINICAL HEALTH (ORGANS, DISEASES AND ABNORMAL CONDITIONS)&rft_subject=Expanding Knowledge in the Biological Sciences&rft_subject=EXPANDING KNOWLEDGE&rft_subject=EXPANDING KNOWLEDGE&rft.type=dataset&rft.language=English Access the data
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High-throughput patch clamp electrophysiology dataset acquired on Nanion syncropatch 384PE platform describing voltage dependent gating of hERG potassium channels expressed in HEK cells. Specific voltage protocols: 1) Steady state activation 2) Steady state deactivation 3) Onset of inactivation This example dataset accompanies the methods paper: Heterozygous KCNH2 variant phenotyping using Flp-In HEK293 and high-throughput automated patch clamp electrophysiology by Chai-Ann Ng, Jessica Farr, Paul Young, Monique J. Windley, Matthew D. Perry, Adam P Hill, View ORCID ProfileJamie I Vandenberg. Preprint available at : https://doi.org/10.1101/2021.02.02.427891

Issued: 2021

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Subjects
Animal Physiology - Biophysics | Biological Sciences | Cardiorespiratory Medicine and Haematology | Clinical Health (Organs, Diseases and Abnormal Conditions) | Cardiology (Incl. Cardiovascular Diseases) | Cardiovascular System and Diseases | Expanding Knowledge | Expanding Knowledge | Expanding Knowledge in the Biological Sciences | Health | Medical and Health Sciences | Physiology | cardiac arrhythmia | electrophysiology | hERG | ion channel | patch clamp |

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Identifiers
ACN 633 798 857