The effects of phencyclidine on the NMDA receptor-neuregulin1 signalling complex: implications for schizophrenia [ 2009 - 2012 ]

Also known as: NMDA receptor-neuregulin1 signalling in response to phencyclidine administration

Research Grant

[Cite as]

Researchers: Prof Xu-Feng Huang (Principal investigator) ,  A/Pr Kelly Newell

Brief description Phencyclidine is the best known pharmacological agent that can induce schizophrenia-like symptoms in humans and animals. Recent research has strongly suggested that neuregulin1 and ErbB4 signalling are involved in schizophrenia pathology. This study will be the first to determine whether neuregulin1 is altered by phencyclidine, which will further our knowledge by re-evaluating the causal role of neuregulin1 in schizophrenia.

Funding Amount $AUD 433,872.39

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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