Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1017798]Researchers: Mr Andrew Farrell (Principal investigator)
Brief description Australia has the highest incidence of skin cancer in the world. SWI/SNF, a yeast nucleosome remodeling complex, is known destabilise interactions in DNA. It is made up of 8-10 proteins, including a novel tumour suppressor Brm. There is some evidence that Brm acts as a tumour suppressor in skin cancer, but relevance of a recently found mutation in Brm is yet to be characterised. This project aims to identify the effect of this mutation, on cellular sensitivity to UV radiation and examine transformation to malignancy.
Funding Amount $AUD 92,314.28
Funding Scheme Postgraduate Scholarships
Notes Dora Lush Biomedical Postgraduate Scholarship
- nhmrc : 1017798
- PURL : https://purl.org/au-research/grants/nhmrc/1017798
