The effects of MDMA in humans [ 2005 - 2006 ]

Research Grant

Researchers: A/Pr Rodney Irvine (Principal investigator) ,  Prof Jason White

Brief description Ecstasy use is growing faster throughout the world than than any other drug of abuse. United Nations figures from 2003 show that it is used by more individuals than the combined total of cocaine and heroin users. Australia has the highest per capita use of 'Ecstasy' in the world with rates twice those of North Americal and Europe. As a result of this we also have a high rate of adverse effects. These can be immediate, and lead to death, or long term leading to brain damage and psychopathologies. So far, no studies have been conducted,anywhere in the world, which have objectively examined the medical effects of 'ecstasy' in the dance clubs where it is used. Because of this, there is a lot of speculation on whether the animal based or hospital based studies are valid and relate to normal recreational use of this drug. This has led to a degree of suspicion by users and health professionals as to the medical problems claimed to be associated with the drug. This project extends a pilot study we undertook which has highlighted that in a recreational setting it is likely that specific individuals are susceptible to damage by 'ecstasy'. The purpose of this project is to examine this in detail, and identify who, and why some young persons are at risk of immediate life threatening outcomes from 'ecstasy' use or may develop brain damage later. The intended outcome is to provide clear evidence of adverse effects and why they occur. This evidence may be used to improve harm minimisation and treatment programs.

Funding Amount $AUD 349,800.00

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant