The effects of maternal infection on glutamate-related behavioural, electrophysiological and neuropathological measures relevant to schizophrenia [ 2012 - 2015 ]

Research Grant

Researchers: E/Pr Patricia Michie (Principal investigator) ,  A/Pr Juanita Todd ,  Dr Katerina Zavitsanou ,  Prof Deborah Hodgson ,  Prof Ulrich Schall

Brief description There are two well known facts about schizophrenia: maternal infection increases the risk of a schizophrenia diagnosis in adulthood and certain drugs, such as PCP, that affect particular brain chemicals induce symptoms and brain changes in healthy individuals that are similar to schizophrenia. Here we bring these two facts together by attempting to develop a maternal infection model in rodents that mimics the brain changes seen in schizophrenia, thus opening up new options for treatment.

Funding Amount $AUD 533,136.18

Funding Scheme Project Grants

Notes Standard Project Grant