The Effects of Human Epilepsy Mutations on Synaptic GABA-A Receptors Studied by Localization-based Superresolution Microscopy [ 2018 - ]

Research Grant

Researchers: Prof Joseph Lynch (Principal investigator) ,  Dr Nela Durisic

Brief description The genetic epilepsies are debilitating neurological disorders that are frequently associated with mutations in genes encoding neurotransmitter-gated receptors in the brain. The goal of this project is to understand mechanisms that cause changes in neuronal communication and lead to epilepsy on a single receptor level. This will lead to an improved understanding of the mechanisms of epileptogenesis and new insights into ways of treating different epilepsies.

Funding Amount $516,978.00

Funding Scheme Project Grants

Notes Standard Project Grant