grant

Effects of Ephrin-Eph and PTHrP signalling on osteosarcoma. [ 2010 - 2012 ]

Also known as: Growth and spread of bone cancer

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/620203]

Researchers: E/Pr Thomas Martin (Principal investigator) ,  A/Pr Carl Walkley A/Pr Janine Danks

Brief description Osteosarcoma (OS) is the most common bone cancer in children, with ~170 cases per year in Australia. We used genetic mutation of mice to induce OS that is very similar to human OS. The OS produces parathyroid hormone-related protein and ephrins and responds to both proteins. We will study how the cancer develops and spreads, and how this is affected by these two pathways, both of which are implicated in cancer development, and could be targets for treatment.

Funding Amount $AUD 646,486.28

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]