Effectiveness of Mindfulness Based Cognitive Therapy for Preventing Depressive Relapse in Subjects at Very High Risk [ 2007 - 2011 ]

Research Grant

Researchers: Prof Graham Meadows (Principal investigator) ,  Prof Fiona Judd ,  Prof Leon Piterman ,  Prof Paul Martin ,  Prof Zindel Segal

Brief description More than one in twenty Australians experience depression in a single year and it is commonly a relapsing disorder. At least 60% of people who have had a depressive episode will have another, the vast majority within two years of the index episode, 70% of those who have had two episodes will have a third, and 90% of those with three episodes will have a fourth. The economic burden of depression in Australia has been estimated as perhaps $2.8 billion annually. Mindfulness-based cognitive therapy (MBCT) is an innovative psychological treatment, combining principles of cognitive therapy and mindfulness meditation. It is designed to prevent depressive relapse in people who have recovered from depressive episodes. MBCT aims to teach people to become more aware of, and to relate differently to, their thoughts, feelings and bodily sensations; in particular, to view these thoughts and feelings as passing events in the mind rather than identifying with them. Through gaining these skills in increased awareness of thoughts and feelings, participants in the treatment learn to avoid negative ruminations, which have a powerful role in triggering relapses of depression. Primarily this study aims to examine the effectiveness of MBCT for the first time in Australians with a history of recurring depression. As a large multi-site investigation it will establish the feasibility of bringing MBCT into routine practice in both urban and rural areas of Australia. The study also aims to establish whether the mechanisms by which MBCT is proposed to work - by decreasing rumination, increasing levels of mindfulness and self-awareness - do in fact operate. We also hope to establish whether MBCT also has any impact on anxiety, another disabling condition that commonly occurs with depression. This study will enhance evidence as to whether the treatment of MBCT should be recommended routinely to sufferers with repeated episodes of major depression.

Funding Amount $AUD 643,317.64

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant