grant

The effect of metals on neurofibrillary tangle formation [ 2008 - 2010 ]

Also known as: The effect of metals on Alzheimers disease pathology

Funded by National Health and Medical Research Council
Managed by The University of Melbourne
Managed by University of Melbourne
Provided by   National Health and Medical Research Council

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/509276]

Researchers: A/Pr Paul Adlard (Principal investigator)

Brief description The majority of studies into Alzheimer's disease (AD) have focussed on two brain lesions- the plaque and neurofibrillary tangle (NFT), which are believed to have a causative role in AD. Our lab has made several seminal discoveries about the role that metals play in the development of plaques. We are now extending this work to evaluate the role of metals in NFT formation. These studies will provide insight into the formation and possible treatments for this primary brain lesion in AD.

Funding Amount $AUD 333,313.54

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant

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Subjects
Alzheimer's disease | Animal model | Biomedical and Clinical Sciences | Disease models, animal | Medical Infection Agents (Incl. Prions) | Medical Microbiology | Metals | Neurofibrillary tangles | Tau |
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