grant

The effect of Cytochrome P450 genotype on blood pressure and 20-HETE responses to lifestyle interventions [ 2010 - 2013 ]

Also known as: The effect of genetic background on blood pressure response to lifestyle intervention

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/634359]

Researchers: Prof Anne Barden (Principal investigator) ,  Dr Natalie Ward E/Pr Lawrie Beilin Prof Ian Puddey Prof Kevin Croft

Brief description The effectiveness of treatments to reduce heart disease risk can vary enormously between individuals. This is partly due to a persons genetic makeup. Fatty acid metabolites called cytochrome P450 metabolites of arachidonic acid (CYP450-AAM) can act on blood vessels and the kidney to regulate blood pressure. We will study the effect of having a variation in a gene that regulates CYP450-AAM on blood pressure and heart disease risk in combination with a high salt diet or weight reduction.

Funding Amount $AUD 743,665.56

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

Click to explore relationships graph
Identifiers
Viewed: [[ro.stat.viewed]]