grant

Effect of anti-IgE antibody on immune system responses and short-term outcome in acute asthma in children [ 2015 - ]

Also known as: 5015945

Research Grant

[Cite as http://purl.org/au-research/grants/nhmrc/GNT1087700]

Researchers: Prof Peter Le Souef (Principal investigator) ,  A/Pr Guicheng Zhang Dr Andrew Currie Dr Anthony Bosco Dr Ingrid Laing
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Brief description We plan to undertake a randomised, double-blind, placebo-controlled, clinical trial of anti-IgE antibody given at the time of an acute attack of asthma in children aged 6-12 years. The idea for this arose from our own novel data – IgE levels increase with the most common infection causing acute asthma. Given evidence the virus uses IgE to cause inflammation, giving anti-IgE during the attack should reduce the severity of the attack and produce a new, effective treatment for acute asthma.

Funding Amount $547,648.00

Funding Scheme Project Grants

Notes Standard Project Grant

Identifiers
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