grant

Effect of aging and mitochondrial dysfunction on the optic nerve response to pressure-induced oxidative stress [ 2008 - 2010 ]

Also known as: Aging and the vulnerability of the optic nerve to damage.

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/475603]

Researchers: Prof Jonathan Crowston (Principal investigator) ,  A/Pr Bang Bui A/Pr Ian Trounce Prof Algis Vingrys

Brief description The risk of glaucoma, a potentially blinding disease of the optic nerve, increases exponentially with age, but the cellular mechanisms responsible are not known. We hypothesise that age-related changes in mitochondria, the energy producing part of the cell, render nerve cells prone to damage. This project will determine whether aging and mitochondrial impairment increase nerve damage and whether dietary moodifications that preserve mitochondria during aging, protect the optic nerve from damage

Funding Amount $AUD 415,554.27

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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