eEF1A1 is critical for HIV-1 reverse transcription and replication [ 2015 - 2017 ]

Research Grant

Researchers: A/Pr David Harrich (Principal investigator) ,  Dr Dongsheng Li ,  Prof Sally-Ann Poulsen

Brief description The project will investigate interaction between the AIDS virus, HIV-1, and the human cell it grows in specifically focusing on a human protein called eEF1A. Our research shows eEF1A is required for HIV-1 growth by regulating a step in the virus life cycle called reverse transcription. The goal of this project is investigate how interaction with eEF1A helps HIV-1 reverse transcription and to find drugs that block HIV-1 interaction with eEF1A.

Funding Amount $AUD 521,429.78

Funding Scheme Project Grants

Notes Standard Project Grant