Early Goal-Directed Sedation compared with standard care in mechanically ventilated critically ill patients: a prospective multicentre randomised controlled trial. [ 2013 - 2018 ]

Research Grant

Researchers: Prof Yahya Shehabi (Principal investigator) ,  A/Pr Ian Seppelt ,  Dr Colin Mcarthur ,  Ms Belinda Howe ,  Prof Michael Bailey
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Brief description Almost every patient in intensive care needs sedating drugs for comfort and provision of life-saving treatment. However, sedation causes side effects including coma, delirium and agitation. There is no high-level evidence to help doctors decide which sedatives to choose and the best way to administer them. The SPICE trial will test a new approach called Early Goal-Directed Sedation based on an alternative sedative agent to see whether it delivers safer, targeted light sedation with less delirium.

Funding Amount $AUD 2,890,451.28

Funding Scheme Project Grants

Notes Standard Project Grant