(Dys)Regulating junctional tension: a novel mechanism in tumor cell biology [ 2014 - 2016 ]

Also known as: Cell-cell junction tension and tumor development

Research Grant

[Cite as]

Researchers: Prof Alpha Yap (Principal investigator) ,  Dr Peter Simpson

Brief description This project will study how cancer cells are forced out of their original tissue of origin. This process, called oncogenic extrusion, is important to allow cancer cells to proliferate and invade their surrounding tissue. We have discovered a new cellular mechanism that causes oncogenic extrusion and aim to understand its molecular basis and test how it contributes to breast cancer.

Funding Amount $AUD 732,391.81

Funding Scheme Project Grants

Notes Standard Project Grant

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