The dual-edged sword of zinc as an innate immune antimicrobial weapon against uropathogenic E. coli [ 2018 - ]

Research Grant

Researchers: Prof Matthew Sweet (Principal investigator) ,  Prof Mark Schembri

Brief description Infectious diseases are a major global health threat, and urinary tract infections (UTI) are one of the most common infectious diseases. Most UTI are caused by uropathogenic E. coli (UPEC). In order to cause infections, UPEC must be able to overcome our body’s first line of defence, the innate immune system. This project seeks to understand how our innate immune system uses zinc to combat bacterial infections, and how UPEC is able to defend against such responses in order to cause disease.

Funding Amount $784,428.00

Funding Scheme Project Grants

Notes Standard Project Grant