Dopamine mechanisms conferring resilience to depression: A new antidepressant target [ 2008 - 2011 ]

Research Grant

Researchers: Prof Trevor Day (Principal investigator) ,  A/Pr Doug Smith ,  E/Pr Peter Dunkley ,  Prof David Pow

Brief description A significant proportion of people who suffer depression fail to obtain effective relief from either drugs or psychotherapy. Accordingly, there is a pressing need to develop new, and more effective, treatments. This project will determine whether certain specific brain pathways that use the transmitter dopamine can be manipulated in their activity so as to increase resilience to depression. This work has potential to provide the foundation for the development a new generation of antidepressants.

Funding Amount $AUD 560,948.94

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant