Does vitamin D supplementation prevent progression of knee osteoarthritis? A randomised controlled trial [ 2010 - 2014 ]

Research Grant

Researchers: Prof Changhai Ding (Principal investigator) ,  A/Pr Anita Wluka ,  Dr Stephen Quinn ,  Prof Flavia Cicuttini ,  Prof Graeme Jones
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Brief description Observational evidence suggests that vitamin D deficiency may have a role in the causes of osteoarthritis (OA) and there are biologically plausible mechanisms to explain this. There is, however, no evidence which shows that intervening with vitamin D supplementation can slow the progression of OA. This study will compare knee OA structural changes in patients receiving vitamin D supplementation with those receiving a placebo. Use of MRI will provide sensitive measures of knee OA changes.

Funding Amount $AUD 1,016,758.48

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant