Does statin use have a disease modifying effect in symptomatic knee osteoarthritis? A multicentre randomised, double-blind, placebo-controlled trial [ 2013 - 2017 ]

Research Grant

Researchers: Dr Yuanyuan Wang (Principal investigator) ,  Prof Andrew Tonkin ,  Prof Catherine Hill ,  Prof Changhai Ding ,  Prof Flavia Cicuttini
View all 6 related researchers

Brief description Osteoarthritis (OA) is a major cause of knee pain and disability. Treatments are limited to reducing pain and improving function: no therapy slows disease progression, with symptomatic end-stage OA treated by knee replacement. Statins, a drug class used to lower cholesterol levels, may affect the structural progression in knee OA. We propose a randomised controlled trial to see if statin use slows the progression of knee OA, which would delay or prevent the need for joint replacement.

Funding Amount $AUD 1,002,987.68

Funding Scheme Project Grants

Notes Standard Project Grant