Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/491133]Researchers: Prof Christopher Sobey (Principal investigator) , Dr Alyson Miller , Prof Grant Drummond
Brief description This project will assess whether the reduction of a novel mechanism to open brain arteries (i.e. via activation of 'Nox' proteins and generation of oxygen radicals) is a possible explanation of why hormone replacement therapy (HRT) increases the risk of stroke in postmenopausal women. We will compare brain artery function of normal mice with those deficient in certain Nox genes in models of menopause, HRT and stroke. This knowledge should lead to safer stroke therapies in women and men.
Funding Amount $AUD 481,439.08
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 491133
- PURL : https://purl.org/au-research/grants/nhmrc/491133
