Does mitochondrial metabolism in neurons act to link peripheral metabolic state to motivated food-seeking behaviour? [ 2014 - 2019 ]

Research Grant

Researchers: Dr Sarah Lockie (Principal investigator)

Brief description Obesity, and its associated pathologies, is a major disease concern. The brain systems that regulate food intake and body weight break down under the strain of obesity and this creates a vicious cycle where failure to regulate metabolism promotes further weight gain. I am investigating how the mitochondrial enzyme CPT1c regulates these brain systems, and whether obesity impairs CPT1c function. Understanding CPT1c function in the brain will help us understand the causes of obesity and diabetes.

Funding Amount $AUD 335,697.23

Funding Scheme Early Career Fellowships

Notes Peter Doherty Biomedical ECF