grant

How does disruption of Serinc1 expression affect lymphocyte function and the development of autoimmunity? [ 2012 - 2014 ]

Also known as: Serinc1's role in lymphocyte function and autoimmunity

Research Grant

[Cite as https://purl.org/au-research/grants/nhmrc/1030865]

Researchers: Dr Thomas Brodnicki (Principal investigator) ,  Dr Colleen Elso Dr Pablo Silveira Prof Katharina Gaus

Brief description Autoimmune diseases affect up to 8% of the population. We have recently discovered a novel gene mutation in mice that results in increased levels of anti-nuclear antibodies, a hallmark of various autoimmune diseases in humans. The mutated gene, Serinc1, has not been previously implicated in autoimmune disease, but it is important for synthesis of key molecules in immune cells. This research proposal aims to determine how disruption of Serinc1 contributes to the development of autoimmune disease.

Funding Amount $AUD 681,555.05

Funding Scheme Project Grants

Notes Standard Project Grant

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