Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/1108422]Researchers: Prof Christopher Liddle (Principal investigator)
Brief description Non-alcoholic fatty liver disease is the most common liver disease that can progress to non-alcoholic steatohepatitis (NASH), cirrhosis and liver cancer. Dietary cholesterol is a major risk factor for NASH. We can demonstrate that cholesterol changes the gut bacteria. These bacteria generate toxic chemicals (bile acids) that signal to the liver and induce NASH. In this project, we use novel ways to clarify the mechanisms of liver inflammation and test novel therapeutic approaches to reverse it.
Funding Amount $AUD 828,229.27
Funding Scheme Project Grants
Notes Standard Project Grant
- nhmrc : 1108422
- PURL : https://purl.org/au-research/grants/nhmrc/1108422
