Does caffeine affect the development of the very immature brain: dose response relationship? [ 2010 - 2012 ]

Research Grant

Researchers: Dr Mary Tolcos (Principal investigator) ,  A/Pr Jeanie Cheong ,  Dr Robert De Matteo ,  Prof Richard Harding ,  Prof Sandra Rees

Brief description Premature birth is a major health problem worldwide. Preterm babies often develop apnoea of prematurity (AOP), which is commonly treated with caffeine. Trials indicate that preterm babies treated with low dose caffeine have less neurodevelopmental disabilities at 18 months. Higher doses of caffeine are often needed to reduce AOP but the risk of this is unknown. We will study the short and long-term effects of increasing doses of caffeine on the developing brain in a long-gestation species.

Funding Amount $AUD 668,386.85

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant