How does basal chromatic structure predict cytokine gene responses? [ 2008 - 2011 ]

Also known as: Switching genes on in immune cells

Research Grant

[Cite as]

Researchers: Dr Adele Holloway (Principal investigator) ,  Prof Frances Shannon

Brief description To recognise foreign pathogens and eradicate them from the body, immune cells need to quickly switch on genes encoding factors which communicate between cells and drive the immune response. Incorrect expression of these genes contributes to immune diseases such as asthma, arthritis and leukaemia. The aim of this project is to study how the DNA environment of immune genes controls their ability to be switched on and off, and how altering this environment leads to incorrect gene expression.

Funding Amount $AUD 521,961.08

Funding Scheme NHMRC Project Grants

Notes Standard Project Grant

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