How does activated protein C create intact, non-leaky, stable blood vessels? [ 2010 - 2012 ]

Research Grant

Researchers: Prof Christopher Jackson (Principal investigator) ,  Dr Meilang Xue

Brief description Vascular dysfunction is a common feature of many diseases, including sepsis, diabetes, atherosclerosis, tumours and asthma. These vessels have compromised structural and functional integrity, leading to leakage of blood components and causing inflammation in tissues. Based on our recent findings, this project aims to discover how activated protein C creates normal, healthy non-leaky blood vessels and prevents vascular dysfunction in disease.

Funding Amount $AUD 564,644.09

Funding Scheme NHMRC Project Grants

Notes New Investigator Grant