Research Grant
[Cite as https://purl.org/au-research/grants/nhmrc/293810]Researchers: Prof Susan Clark (Principal investigator)
Brief description In this grant we aim to study the moecular basis of cancer. The promoter regions of tumour suppressor genes are often modified in cancer by a chemical process called methylation. Methylation of DNA is associated with gene silencing. Therefore DNA methylation is commonly regarded as causing the silencing of genes in cancer. In this grant, we aim to determine if methylation is causal in triggering gene silencing in cancer, or if methylation is a consequence of gene silencing. This is a critical distinction in understanding the role of methylation in cancer development.
Funding Amount $AUD 333,000.00
Funding Scheme NHMRC Project Grants
Notes Standard Project Grant
- nhmrc : 293810
- PURL : https://purl.org/au-research/grants/nhmrc/293810
